Mouse Monoclonal Antibody to CK7
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| Catalog# |
20401
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| Clone# |
3B9
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| Host and isotype |
Mouse IgG1
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| Species reactivity |
Human
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Lot# |
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| Size |
0.1ml
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Price |
$
280
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| MW |
51kDa
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Entrez Gene |
3855
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| Aliases |
KRT7; cytokeratin 7
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| Description |
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CK7 (Keratin, type II cytoskeletal 7) is a protein that in humans is encoded by the KRT7 gene. CK7 is a member of the keratin family. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.
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| Immunogen |
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Purified recombinant fragment of CK7 expressed in E. Coli.
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| Applications |
Western Blot: 1: 500 - 1: 2,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.
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| Formulation |
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Ascitic fluid containing 0.03% sodium azide.
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| Storage |
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Store at 4℃, for long term storage, store at -20℃.
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| Related product |
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| References |
1. Cytogenet Cell Genet. 1991;57(1):33-8.
2. J Pathol. 1998 Mar;184(3):234-9.
3. J Cell Biol. 2006 Jul 17;174(2):169-74.
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Figure 1: Western blot analysis using anti-CK7 monoclonal antibody against Hela (1), MCF-7 (2), A431 (3) and A549 (4) cell lysate.
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| FOR RESEARCH USE ONLY |
